What is vaccine hesitancy?
Vaccine hesitancy is a delay in the acceptance or refusal of vaccines despite the availability of vaccine services. This topic is complex and context-specific varying across time, place, and vaccines. It is influenced by factors such as complacency, convenience, and confidence.
Source: WHO
Vaccine Hesitancy by County
Click on the county where your Health Center is located on the map above. The above map shows an estimate of COVID-19 vaccine hesitancy rates using data from the U.S. Census Bureau’s Household Pulse Survey (HPS).
For more information, visit the CDC website.
Hesitancy Resources
Websites
1. Kaiser Family Foundation has multiple ongoing research projects tracking the public’s attitudes and experiences with COVID-19 vaccinations.
Scholarly Articles
1. Sources of Vaccine Hesitancy: Pregnancy, Infertility, Minority Concerns, and General Skepticism
Open Forum Infectious Diseases, Volume 9, Issue 3, March 2022
Authors: Albert L Hsu, Traci Johnson, Lynelle Phillips, and Taylor B Nelson
The coronavirus disease 2019 (COVID-19) epidemic continues to evolve, with variants of concern and new surges of COVID-19 noted over the past months. The limited data and evolving recommendations regarding COVID-19 vaccination in pregnancy have led to some understandable hesitancy among pregnant individuals. On social media, misinformation and unfounded claims linking COVID-19 vaccines to infertility are widespread, leading to vaccine skepticism among many men and women of reproductive age. The disproportionate impact of COVID-19 on communities of color, coupled with the unfortunate and troubled history of abuses of African Americans by the biomedical research community in the US, has also led to hesitancy and skepticism about the COVID-19 vaccines among some of our most vulnerable. The complex nature of vaccine hesitancy is evidenced by further divides between different demographic, political, age, geographical, and socioeconomic groups. Better understanding of these concerns is important in the individualized approaches to each patient.
2. Addressing Vaccine Hesitancy
The College of Family Physicians of Canada 2019 Mar; 65(3): 175–181.
Authors: Shixin Shen and Vinita Dubey
Practical tips for addressing parental vaccine hesitancy in primary care include starting early, presenting vaccination as the default approach, building trust, being honest about side effects, providing reassurance on a robust vaccine safety system, and focusing on the protection of the child and community, telling stories, and addressing pain. Also provided are statements that providers could use in vaccination-related conversations; answers to commonly asked questions on benefits, safety, and immunologic aspects of vaccines; and links to a number of online resources for physicians and parents.
Websites
1. Vaccine Hesitancy in Rural America
Kaiser Family Foundation presents vaccine hesitancy data among rural communities and effective messages for rural Americans.
2. Vaccine Information Resources for Farmers
Scholarly Articles
1. COVID-19 Testing and Vaccine Hesitancy in Latinx Farm-Working Communities in the Eastern Coachella Valley
National Institute of Health June 25 2021
Authors: Daniel Gehlbach, Evelyn Vázquez, Gabriela Ortiz, Erica Li, Cintya Beltrán Sánchez, Sonia Rodríguez, María Pozar, and Ann Marie Cheney
Gehlbach et al. (2021) discusses misinformation, lack of trust in institutions, and insecurity among Latinx immigrants in rural agricultural communities.
PDFs
1. COVID-19 Vaccination Field Guide Addendum: Rural Considerations for Vaccine Confidence and Uptake Strategies
The CDC presents 12 evidence-based strategies to increase COVID-19 confidence and uptake in rural communities with the help of rural health organizations. s
Websites
1. Join CDC in Promoting National Minority Health Month: Give Your Community A Boost!
2. Introduction to COVID-19 Racial and Ethnic Health Disparities
The CDC discusses health inequities that have disproportionally affected minorities in the United States. They have provided definitions, issues, and more resources surrounding this topic.
Scholarly Articles
1. Confidence and Hesitancy During the Early Roll-out of COVID-19 Vaccines Among Black, Hispanic, and Undocumented Immigrant Communities: a Review
Journal of Urban Health volume 99, pages 3–14 (2022)
Authors: SarahAnn M. McFadden, Jemal Demeke, Debbie Dada, Leo Wilton, Mengzu Wang, David Vlahov & LaRon E. Nelson
Black and Hispanic Americans have been hardest hit with COVID-19 infections, hospitalizations, and deaths, yet during the first several months of vaccine roll-out they had the lowest level of vaccine uptake. Primarily, our research on vaccine hesitancy focused on skepticism around the vaccine itself and its roll-out. Our search strategy used PUBMED and Google with a prescribed set of definitions and search terms for two reasons: there were limited peer-reviewed studies during early period of roll-out and real-time perspectives were crucially needed. Literature searches occurred in April 2021and covered September 2020-April 2021. Analyses included expert opinion, survey results and qualitative summaries. Overall, for the general U.S. population, there was considerable hesitancy initially that remained high during the early roll-out. The general population expressed concerns over the speed of vaccine development (“warp speed”), confidence in the competence of government being involved in the development of vaccines and general mistrust of government. Among Black and Hispanic Americans, hesitancy was further expressed as mistrust in the medical establishment that was related to past and current medical mistreatment. Undocumented immigrants worried about access to insurance and possible deportation. These results on confidence in the vaccine early during vaccine roll-out suggest diverse reasons that influence a person’s decision to vaccinate or not. Additional barriers to vaccine uptake include complacency and access. To ensure health equity, particularly to address disparities in morbidity and mortality, vaccine hesitancy needs to be acknowledged and addressed as COVID-19 vaccine roll-out continues, and these observations calls for conscious planning to address these issues early with future health crises.
2. COVID-19 vaccination hesitancy in Hispanics and African-Americans: A review and recommendations for practice
Brain, Behavior, Immunity Journal 2021 Aug; 15
Authors: Jagdish Khubchandania and Yilda Maciasb
COVID-19 vaccines were approved for use in the general American public by late 2020 and early 2021. Media reports started highlighting COVID-19 vaccination hesitancy in racial and ethnic minorities. However, little is known about the extent of COVID-19 vaccination hesitancy in racial and ethnic minorities and whether there are unique sociodemographic and cognitive correlates associated with vaccine hesitancy. Thus, the purpose of this study was to review all nationwide studies on COVID-19 vaccine hesitancy among African-Americans and Hispanics (the largest minority groups in the U.S.). A comprehensive review of the published literature was conducted to search for national studies and a final pool of 13 studies (n = 107,841 participants) was included in this review. The overall pooled prevalence rate of COVID-19 vaccination hesitancy for adult Americans across all studies was 26.3% (95%Ci = 17.3–36.4). In contrast, the overall pooled prevalence rate of COVID-19 vaccination hesitancy for African-Americans was 41.6% (95%Ci = 34.4–48.9) and for Hispanics, it was 30.2% (95%Ci = 23.2–37.7). The major predictors of vaccine hesitancy in African-Americans and Hispanics were: sociodemographic characteristics (e.g., age, gender, income, education, and household size); medical mistrust and history of racial discrimination; exposure to myths and misinformation, perceived risk of getting infected with COVID-19; beliefs about vaccines and past vaccine compliance, and concerns about the safety, efficacy, and side effects from the COVID-19 vaccines. Given the high COVID-19 vaccine hesitancy rates in racial/ethnic minorities and the unique factors associated with vaccine hesitancy in African-Americans and Hispanics, several clinic-based and community-oriented practice recommendations have been included in this article.
Website Articles
1. Kids’ COVID-19 vaccines are available. So why are parents’ concerns still so high?
Scholarly Articles
1. Vaccine Hesitancy and Refusal
The Journal of Pediatrics Volume 175, P248-249.E1, August 01, 2016
Authors: E. David G. McIntosh, MBBS, MPH, LLM, PhD Jan Janda, MD Jochen H.H. Ehrich, MD, DCMT Massimo Pettoello-Mantovani, MD, PhD Eli Somekh, MD
McIntosh et al. (2016) discusses general pediatric vaccine hesitancy and refusal phenomenon. Researchers define pediatric vaccine hesitancy, and discuss the political and social aspects, ethics, and consequences of this phenomenon prior to the COVID-19 pandemic.
2. COVID-9 Pediatric Vaccine Hesitancy among Racially Diverse Parents in the United States
Vaccines (Basel). 2022 Jan; 10(1): 31.
Authors: Celia B. Fisher, Aaliyah Gray, and Isabelle Sheck
On 29 October 2021, the U.S. FDA authorized the Pfizer-BioNTech COVID-19 (SARS-CoV-2) vaccine for emergency use in children ages 5–11 years. Racial/ethnic minorities have born the greatest burden of pediatric COVID-19 infection and hospitalization. Research indicates high prevalence of parental vaccine hesitancy among the general population, underscoring the urgency of understanding how race/ethnicity may influence parents’ decision to vaccinate their children. Two weeks prior to FDA approval, 400 Hispanic and non-Hispanic Asian, Black, and White parents of children 5–10 years participated in an online survey assessing determinants of COVID-19 pediatric vaccine hesitancy. Compared to 31% Black, 45% Hispanic, and 25% White parents, 62% of Asian parents planned to vaccinate their child. Bivariate and multivariate ordinal logistic regression demonstrated race/ethnicity, parental vaccine status, education, financial security, perceived childhood COVID-19 susceptibility and severity, vaccine safety and efficacy concerns, community support, and FDA and physician recommendations accounted for 70.3% of variance for vaccine hesitancy. Findings underscore the importance of multipronged population targeted approaches to increase pediatric COVID-19 vaccine uptake including integrating health science literacy with safety and efficacy messaging, communication efforts tailored to parents who express unwillingness to vaccinate, and interventions developed in partnership with and delivered through existing trusted community coalitions.
3. Parental Vaccine Hesitancy: Clinical implications for Pediatric Providers
Journal of Pediatrics Volume 29, Issue 4, P385-394, 01 July 2015
Authors: Meagan A. Barrows, BSN, RN Jennifer A. Coddington, DNP, MSN, RN, CPNP Elizabeth A. Richards, PhD, MSN, RN, CHES Pamela M. Aaltonen, PhD, RN
Despite being recognized as one of the greatest public health achievements, vaccines are increasingly under scrutiny for a multitude of reasons. “Parental vaccine hesitancy,” an emerging term in today’s literature, encompasses a wide range of concerns regarding vaccines and is believed to be responsible for decreasing coverage of many childhood vaccines. The threat to herd immunity posed by poor vaccine uptake increases the risk for resurgence of vaccine-preventable diseases. Pediatric primary health care providers have an obligation to respond to the increasing prevalence of vaccine hesitancy by providing education related to vaccines to ensure the safety and health of the population. The purpose of this article is to examine the most common concerns surrounding vaccine hesitancy and outline strategies for pediatric providers to address concerns with parents in the clinical setting.
Website Articles
1. Four reasons for COVID-19 vaccine hesitancy among health care workers, and ways to counter them
- Safety and efficacy concerns
- Preference for physiological immunity
- Distrust in government and health organizations
- Autonomy and personal freedom
2. Unpacking Vaccine Hesitancy Among Healthcare Providers
Scholarly Articles
1. Healthcare Providers’ Vaccine Perceptions, Hesitancy, and Recommendation to Patients: A Systematic Review
Misinformation and Combating Misinformation
According to the CDC, misinformation is false information spread by people who do not intend t mislead others. Disinformation is false information intentionally created and spread with harmful intent. Both have been affecting vaccine confidence and vaccination rates as the misinformation and disinformation circulating focused on vaccine development, safety, effectiveness, and COVID-19 denialism. Misinformation is created and circulates when there are information gaps or uncertain science because it is human nature to seek answers in order to better understand and fill in gaps.
Source: CDC
Website Articles
1.Talking to vaccine skeptics in rural, conservative America
2. Meeting COVID-19 Misinformation and Disinformation Head-On
Websites
1. How to Address COVID-19 Vaccine Misinformation
2. Achieving Vaccine Equity: Resources & Best Practices to Bringing Down Barriers
Scholarly Articles
1. Clinical data to be used as a foundation to combat COVID-19 vaccine hesitancy
National Library of Medicine, 12.11.2021
Author: Robert G Smith
The coronavirus has become the paramount subject in peoples’ lives, affecting and disrupting virtually every aspect of society, as the pandemic casts a shadow over the world. The facts, myths, and conspiracy theories centered on the Covid-19 pandemic have dominated social media accounts, local and national newspapers, as well as television programs. Strategies need to be evolved to counter Covid-19 vaccine hesitancy and mitigate health disparities in at-risk populations. Overcoming misinformation and distrust will require an interdisciplinary approach to deal with Covid-19. The purpose of this review is to offer a factual basis to all healthcare providers to assist in framing strategies to mitigate vaccine hesitancy and achieve herd immunity to combat the deadly Covid-19 pandemic. First an overview of the discovery of the viruses and their molecular structures will be presented. Secondly, a historical perspective is offered, comparing the differences between the 1918 flu pandemic and the current covid-19 pandemic. Lastly, an overview for proposed techniques and methods to counter and or mitigate covid-19 vaccine misinformation that may be used by an interdisciplinary team will be offered narratively and graphically.
2. Considerations for addressing anti-vaccination campaigns: How did we get here and what can we do about it?
American Society for Clinical Pharmacology and Therapeutics, 03.21.22
Authors: Jeffery S Barrett, Scarlett Y Yang, Kavitha Muralidharan, Victoria Javes, Kemi Oladuja, Maria Sofia Castelli, Nicole Clayton, Jiaqi Liu, Andre Ramos
A course on vaccine development asked students to write a blog addressing general anti-vaccination strategies and their significance today, in the context of the resistance seen against novel SARS-CoV-2 mRNA vaccines. This perspective explores how and why these efforts are successful at reducing vaccine uptake and why, for the most part, efforts to combat the movement have been unsuccessful. This summary of the collective view of the class provides recommendations for combatting current and future campaigns of misinformation. It is hoped that this perspective will serve as a call to action for clinical pharmacologists and translational scientists to do their part to educate the lay community and promote the science in an open and transparent manner to ensure that current and future vaccines fulfill their potential.
The webinar titled Weathering the Storm: All hands on deck response to the COVID19 infodemic and how we can prepare for the future held on February 9, 2022 was closed on March 9, 2022; however, there is a summary of the content below.
Dr. Katelyn Jetelina is an epidemiologist who created Your Local Epidemiologist to translate public health science for the public. She recognized two gaps, and the first one was scientific translation can lead to biased reports creating misinformation that causes confusion, anxiety, and people to stop listening. There was no platform for direct communication from scientists, and scientists relied on the media which created intrinsic bias and incorrect summaries.
How people behave matters because infectious diseases violate the assumption of independence, meaning that one person’s actions can put multiple people at risk, and it becomes a public health issue. An infodemic is an overabundance of information where it is hard to find reliable sources and guidance. Misinformation is created by the infodemic as inaccurate information is shared unconsciously and consciously. A study done by Islam et al. (2020) studied the amount of misinformation spread related to COVID-19, and the United States ranked second behind India and in front of China and Spain. This infodemic and its consequences caused suboptimal control of the pandemic, for example, disruption in the toilet paper supply chain, crowded train stations to escape lockdowns, and overdosing on medicines that were believed to be the cure for COVID-19.
Dr. Jetelina offers four ways of combating the COVID-19 infodemic. The first is knowing the landscape and understanding that the information ecosystem is changing. Thirty percent of Americans trust the news, and the most used source for health is the internet (73%). In a study done by Voshoughi et al. (2018) the spread of misinformation compared to the truth reached far more people, was retweeted by more people, spread through peer-to-peer, six times faster at spreading, retweeted by more unique users, and diffused more broadly. This is explained by the fact that there is an emotional relationship to information. Language plays on fear, which gets higher engagement on social media platforms. Vaccines and deaths related to COVID-19 had the most engagement. Also, misinformation easily circulates on social media groups or platforms that feel like safe spaces, meaning that the public will potentially be bad at assessing risk.
The second is recognizing what is spreading and listening to what people are saying about COVID-19. There are legitimate concerns that exist, so look for questions that can be answered to educate others and open a tip line. It is also important to understand where people are talking
The third is recognizing the kernel of truth. The media can draw the wrong conclusions and not provide the right context when discussing information and facts. The first example is the CDC published a table which showed that 4,178 Americans died following experimental COVID-19 injections, and someone published an article linked to these findings saying that vaccines were killing people. However, it is an inaccurate conclusion because deaths from COVID-19 vaccines would equal 20 years of recorded deaths following vaccines since 2001. Another example is a German epidemiologist claimed that the COVID-19 vaccine causes miscarriages because the vaccine causes women’s bodies to reject a protein connected to the placenta. The truth is that the receptor on the placenta is like the spike protein in the vaccine; however, not similar enough to cause confusion and cannot get confused. Therefore, not causing a miscarriage.
The fourth is start combating by leading with the truth. It is okay to not have all the answers, and it is better to be transparent. Dr. Jetelina also recommends offering alternative explanations when people have concerns. Going back to the reported 4,178 deaths from the CDC, this data comes from the VAERS honor system, which can contain information that is incomplete, inaccurate, coincidental, or unverifiable. Meaning that inclusion of events in VAERS data does not imply causality. Another example is people having concerns over the long-term outcomes of the mRNA vaccine. An alternative explanation is that the vaccine ingredients clear from the body quickly. The mRNA component of the vaccine is cleared after 72 hours, and the fat bubbles take about 4 days to clear. Vaccines have also been studied for many years, and vaccine side effects occur within 6 to 8 weeks of inoculation. Another inaccurate conclusion that spread throughout the media was that mRNA would change our DNA. An alternative explanation is that mRNA cannot be converted to DNA because that would require reverse transcriptase, which the vaccine does not contain. The mRNA found in the vaccine cannot insert itself into the DNA either because it would need integrase, which the vaccine also does not contain. Transcriptase and integrase are tools used during DNA replication.
Dr. Jetelina highlights some valuable information surrounding the anti-vax community that are alternative explanations as to why they chose this position. The anti-vax community makes about $36 million per year in revenue, and is worth up to $1 billion in big tech. There are also four prominent families that control the anti-vax conversations. For more information read this article by the Center for Countering Digital Hate.
Finally, Dr. Jetelina describes how important language matters when discussing misinformation and conspiracies. She acknowledges that our world view is linked to identity and the communities that we are a part of. Relationships and knowledge cannot be built using words and attitudes like dumb, insane, and bizarre, which is why it is important to choose your words wisely when discussing misinformation. It is important to be proactive instead of reactive because under 5 COVID-19 vaccines will be authorized soon, and it is important to address parental concerns and communicate the proper facts and information. It is also important as this may not be the last pandemic we see in our society as there will be more viruses due to climate change, globalization, and transmission from animals to humans. It is important that science is available in every community, and that the public is knowledgeable and involved in research.
Summary:
- Communicate the threat clearly. Most Americans get their news and health information from social media
- Address the circulating misinformation
- Engage with community stakeholders to amplify evidence-based information through grassroots networks
- Improve health communication
- Listen
Transmission Interrupted
Lauren Sauer, Association Professor at the College of Public Health, Department of Environmental, Agricultural, and Occupational Health, at the University of Nebraska Medical Center, hosts this podcast with guest speakers, Jacinda Abdul-Mutakabbir, Assistant Professor of Pharmacy Practice at Loma Linda University, Precious Davis, a nurse case manager, and Dr. Jasmine Marcelin, an infectious disease doctor. These health professionals discuss multiple approaches to combating vaccine hesitancy. Vaccine hesitancy does not mean that someone is inherently wrong because there is a continuum of attitudes, which is why negative attitudes should never be assumed as patients could just have questions.
Empathy Perspective:
Approach patients from the perspective of wanting to understand where they lack the confidence to get the vaccine
Discuss important parts of the COVID-19 vaccine as it relates to the number of minorities in the vaccine clinical trials, historical events (Tuskegee), and that the vaccine is not a placebo
One healthcare worker discussed her religion believes that being vaccinated means they are “marked by the beast”
Discuss personal hesitations in order to combat making them feel bad about the way they feel
Motivational Interviewing:
Open-ended questions for the patients rather than providing information that the patient may not want
Do not go into the discussion with biases
Go into conversation with zero expectations and try and figure out what makes them perceive the vaccine in the way that they do
“What are your thoughts/feelings/emotions surrounding the COVID-19 vaccine?”
“What do you know about the COVID-19 vaccine, and where do you get your information from?”
Ask about family history or patient history of vaccine hesitancy
Ask them about their values and what is important to them, which gives the patient a voice to discuss the topic
Ask permission if you (the provider) may share data/personal information
Provide available up-to-date data including vaccination rates, death, comorbidities, complications
Discussing Mandates
Should not take away from knowledge and education
Do not want negativity surrounding vaccine because they are forced to by job/ to go places
WANT patients to understand why vaccines are important on an individual and population level to change attitudes (discuss protection and other knowledge so that people are like I got the vaccine because I wanted to and was given all the information in order to consent)
Advancing Health Podcast
Julia Resnick, director of strategic initiatives at the American Hospital Assocation, hosts this podcast with guest speaker, Lydia Isaac, who is the Vice President for Health Equity and Policy at the National Urban League. Isaac discusses that many Americans who are hesitant to get the COVID-19 vaccine may feel forced by mandates and restrictions and may not understand why vaccines are important for protecting the general public. She discusses the lack of trust in the COVID-19 vaccine from the Black community stemming from who the science comes from and not necessarily trusting science. Other challenges regarding combating vaccine hesitancy are the abundance of evolving knowledge that is not experts changing their minds, but rather new information causing changes.
Advancing Health Podcast
Priya Bathija, vice president of strategic initiatives at the American Hospital Assocation, hosts this podcast with guest speaker, Juliet K. Choi, who is the President and CEO of the Asian & Pacific Islander American Health Forum. Juliet discusses how language and culture matters when it comes to discussing the pediatric COVID-19 vaccines. When considering discussing pediatric COVID-19 vaccines, health providers may want to try family-oriented messaging. Some challenges are that there needs to be updated information that is digestible, information that is available in a timely manner, and information in other languages. This would require change from a local level where there were investments into time and energy of the people providing this COVID-19 vaccine messaging.
Short Wave by npr
Emily Kwong hosts this podcast with guest speaker, Dr. Jasmin Marcelin, who is an infectious disease specialist. Dr. Marcelin discusses how important it is to listen to what the patient believes about the pandemic and virus in order to help health professionals understand what they will need to do. There is not going to be just one discussion most of the time, and there should be no expectations going into the conversation. Having meaningful conversations with patients can be beneficial to the public because those patients will spread this information with their friends, and more people will become informed through these conversations. Also, people will be able to distinguish misinformation as they learn more and have more open discussions with health professionals.
The Dose
Shanoor Seervai, researcher, writer, and lead podcast producer at The Commonwealth Fund, hosts this podcast with guest speakers, Dr. Michelle Fiscus, pediatrician and American Academy of Pediatrics board member, and Rachel Nuzum, employee at the Commonwealth Fund. Pediatric vaccine hesitancy concerns among parents are that the vaccine was created too quickly with not enough testing, and that there are no studies on the long-term effects of the COVID-19 vaccine. Experts recommend pediatric doctors being the main providers of COVID-19 vaccine as parents are more likely to trust the medical professional most involved in their child’s health.
Health & Veritas
Howard Forman and Harlan Krumholz, Yale physician-professors, host this podcast with guest speaker Dr. Saad Omer, director of the Yale Institute for Global Health. Around the 13:50 mark of the podcast is when they begin discussing vaccine hesitancy. Dr. Omer discusses how barriers to vaccination programs need to be met with agility, ingenuity, and adaptiveness. It is important to approach risk taking by failing fast and making changes in a timely manner. Hindsight, Dr. Omer discusses how there was no national immunization plan for a year, lack of money for vaccine acceptance, federal communication, and not reaching people online. The people who the federal government was reaching are the ones who already had opinions. Healthcare providers have access to evidence-based communication science where they would acquire the skills to be candid and proactive in studying and communicating side effects. He discusses the importance of being transparent about vaccine safety, and to never give false reassurance.